Acteurs : Acteur Joseph ABECASSIS

Dr Joseph ABECASSISCentre Paul StraussLaboratoire de Biologie Tumorale 3 rue de la Porte de l’HôpitalBP 42

67065 Strasbourg cedex

Tel : +33 3 88 25 24 43

e/m : [email protected]

Equipe de recherche
Equipe A04 – Joseph ABECASSIS •
Aires d’expertise
Clinique:Biochimie et Biologie MoléculaireCancer:VADS
Axes du CGE
4 : Contrôle de la dissémination tumorale – Plasticité cellulaire, hétérogénéité tumorale et réaction stromale
Equipe A04

  • Sébastien GUIHARD
  • Alain JUNG
  • Régine MILLON
Equipe A04

2008 – APPBP1-VADS (porteur : Sébastien GUIHARD)
Rôle de APPBP1 dans la radiosensibilité des tumeurs de l’oropharynx infectées par HPV
Novel prostate cancer serum markers – validation and development of ultrasensitive nanobead technology and ELISA screens
2007 – RIO2007 (porteur : Marie-Christine RIO)
Early determination of aggressiveness of primary tumors
2005 – TLL12 (porteur : Bohdan WASYLYK)
Evaluation of the therapeutic, prognostic and diagnostic potential of KIAA0153, a novel putative tubulin tyrosine ligase implicated in cancer
2004 – RIO2004 (porteur : Marie-Christine RIO)
Nature and function of the molecular actors involved in local tumor invasion

Rickman DS, Millon R, De Reynies A, Thomas E, Wasylyk C, Muller D, Abecassis J, Wasylyk B. Prediction of future metastasis and molecular characterization of head and neck squamous-cell carcinoma based on transcriptome and genome analysis by microarrays. Oncogene. 2008 Nov 20;27(51):6607-22. Epub 2008 Aug 4.

Muller D, Millon R, Theobald S, Hussenet T, Wasylyk B, du Manoir S, Abecassis J. Cyclin L1 (CCNL1) gene alterations in human head and neck squamous cell carcinoma. Br J Cancer. 2006 Apr 10;94(7):1041-4.

Seghatoleslam A, Zambrano A, Millon R, Ganguli G, Argentini M, Cromer A, Abecassis J, Wasylyk B. Analysis of a novel human gene, LOC92912, over-expressed in hypopharyngeal tumours. Biochem Biophys Res Commun. 2006 Jan 6;339(1):422-9. Epub 2005 Nov 14.

Carles A, Millon R, Cromer A, Ganguli G, Lemaire F, Young J, Wasylyk C, Muller D, Schultz I, Rabouel Y, Dembele D, Zhao C, Marchal P, Ducray C, Bracco L, Abecassis J, Poch O, Wasylyk B. Head and neck squamous cell carcinoma transcriptome analysis by comprehensive validated differential display. Oncogene. 2006 Mar 16;25(12):1821-31.

Lapouge G, Millon R, Muller D, Abecassis J, Eber M, Bergerat JP, Klein-Soyer C. Cisplatin-induced genes as potential markers for thyroid cancer. Cell Mol Life Sci. 2005 Jan;62(1):53-64.

Lemaire F, Millon R, Muller D, Rabouel Y, Bracco L, Abecassis J, Wasylyk B. Loss of HOP tumour suppressor expression in head and neck squamous cell carcinoma. Br J Cancer. 2004 Jul 19;91(2):258-61.

Muller D, Bonaiti-Pellie C, Abecassis J, Stoppa-Lyonnet D, Fricker JP. BRCA1 testing in breast and/or ovarian cancer families from northeastern France identifies two common mutations with a founder effect. Fam Cancer. 2004;3(1):15-20.

Barberi-Heyob M, Vedrine PO, Merlin JL, Millon R, Abecassis J, Poupon MF, Guillemin F. Wild-type p53 gene transfer into mutated p53 HT29 cells improves sensitivity to photodynamic therapy via induction of apoptosis. Int J Oncol. 2004 Apr;24(4):951-8.

Cromer A, Carles A, Millon R, Ganguli G, Chalmel F, Lemaire F, Young J, Dembele D, Thibault C, Muller D, Poch O, Abecassis J, Wasylyk B. Identification of genes associated with tumorigenesis and metastatic potential of hypopharyngeal cancer by microarray analysis. Oncogene. 2004 Apr 1;23(14):2484-98.

Zheng H, Wasylyk C, Ayadi A, Abecassis J, Schalken JA, Rogatsch H, Wernert N, Maira SM, Multon MC, Wasylyk B. The transcription factor Net regulates the angiogenic switch. Genes Dev. 2003 Sep 15;17(18):2283-97.

Redon R, Hussenet T, Bour G, Caulee K, Jost B, Muller D, Abecassis J, du Manoir S. Amplicon mapping and transcriptional analysis pinpoint cyclin L as a candidate oncogene in head and neck cancer. Cancer Res. 2002 Nov 1;62(21):6211-7.
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